A continuous network design model in stochastic user equilibrium based on sensitivity analysis

The continuous network design problem (CNDP) is known to be difficult to solve due to the intrinsic properties of non-convexity and nonlinearity. Such kinds of CNDP can be formulated as a bi-level programme, in which the upper level represents the designer's decisions and the lower level the travellers' responses. Formulations of this kind can be classified as either Stackelberg approaches or Nash ones according to the relationship between the upper level and the lower level parts. This paper formulates the CNDP for road expansion based on Stackelberg game where leader and follower exist, and allows for variety of travellers' behaviour in choosing their routes. In order to solve the problem by the Stackelberg approach, we need a relation between link flows and design parameters. For this purpose, we use a logit route choice model, which provides this in an explicit closed-form function. This model is applied to two example road networks to test and briefly compare the results between the Stackelberg and Nash approaches to explore the differences between them

Distribution of hydrogen peroxide and methylhydroperoxide over the Pacific and South Atlantic Oceans

The gas phase hydrogen peroxide and methylhydroperoxide concentrations were measured in the troposphere over the tropical Pacific Ocean as a component of NASA's Global Tropospheric Experiment/Pacific Exploratory Mission-Tropics A field campaign. Flights on two aircraft covered the Pacific from 70°S to 60°N and 110°E to 80°W and South Atlantic from 40°S to 15°N and 45°W to 70°E, and extending from 76 to 13,000 m altitude. H2O2 and CH3OOH have the highest concentrations at a given altitude at the equator and decrease with increasing latitude in both the northern and southern hemispheres. Above 4 km the gradient is substantially reduced for both H2O2 and CH3OOH with latitude, and at altitudes in excess of 8 km there is no latitudinal dependence. H2O2 and CH3OOH exhibit maximum mixing ratios between 1 and 2 km at all latitudes. The mean mixing ratio of H2O2 at the equator was 1600 ± 600 parts per trillion by volume (pptv) decreasing to 500 ± 250 pptv at latitudes greater than 55° north and south between 1 and 2 km altitude. CH3OOH at the equator was 1400 ± 250 pptv, decreasing to 330 ± 200 pptv at high latitudes at altitudes between 1 and 2 km. The concentration of peroxides at high latitudes in the northern hemisphere was generally a factor of 2 higher than at corresponding latitudes in the southern hemisphere. The ratio of H2O2 to CH3OOH was between 1 and 2 from 45°S to 35°N at altitudes below 4 km. Between 5° to 15°N the ratio is less than 1, due to preferential removal of H2O2 in the Intertropical Convergence Zone. Copyright 1999 by the American Geophysical Union

Stability analysis on a dynamical model of route choice in a connected vehicle environment

Research on connected vehicle environment has been growing rapidly to investigate the effects of real-time exchange of kinetic information between vehicles and road condition information from the infrastructure through radio communication technologies. A fully connected vehicle environment can substantially reduce the latency in response caused by human perception-reaction time with the prospect of improving both safety and comfort. This study presents a dynamical model of route choice under a connected vehicle environment. We analyze the stability of headways by perturbing various factors in the microscopic traffic flow model and traffic flow dynamics in the car-following model and dynamical model of route choice. The advantage of this approach is that it complements the macroscopic traffic assignment model of route choice with microscopic elements that represent the important features of connected vehicles. The gaps between cars can be decreased and stabilized even in the presence of perturbations caused by incidents. The reduction in gaps will be helpful to optimize the traffic flow dynamics more easily with safe and stable conditions. The results show that the dynamics under the connected vehicle environment have equilibria. The approach presented in this study will be helpful to identify the important properties of a connected vehicle environment and to evaluate its benefits

Direct observation of local xylem embolisms induced by soil drying in intact Zea mays leaves

The vulnerability of vascular plants to xylem embolism is closely related to their stable long-distance water transport, growth, and survival. Direct measurements of xylem embolism are required to understand what causes embolism and what strategies plants employ against it. In this study, synchrotron X-ray microscopy was used to non-destructively investigate both the anatomical structures of xylem vessels and embolism occurrence in the leaves of intact Zea mays (maize) plants. Xylem embolism was induced by water stress at various soil drying periods and soil water contents. X-ray images of dehydrated maize leaves showed that the ratio of gas-filled vessels to all xylem vessels increased with decreased soil water content and reached approximately 30% under severe water stress. Embolism occurred in some but not all vessels. Embolism in maize leaves was not strongly correlated with xylem diameter but was more likely to occur in the peripheral veins. The rate of embolism formation in metaxylem vessels was higher than in protoxylem vessels. This work has demonstrated that xylem embolism remains low in maize leaves under water stress and that there xylem has characteristic spatial traits of vulnerability to embolism.117Ysciescopu

Oxygen-Vacancy-Induced Orbital Reconstruction of Ti Ions at the Interface of LaAlO3/SrTiO3 Heterostructures: A Resonant Soft-X-Ray Scattering Study

Resonant soft-x-ray scattering measurements have been performed to investigate interface electronic structures of (LaAlO3/SrTiO3) superlattices. Resonant scattering intensities at superlattice reflections show clear evidence of degeneracy lifting in t(2g) states of interface Ti ions. Polarization dependence of intensities indicates the energy of d(xy) states is lower by similar to 1 eV than two other t(2g) states. The energy splitting is insensitive to epitaxial strain. The orbital reconstruction is induced by oxygen vacancies and confined to the interface within two unit cells, indicating charge compensation at the polar interfaces. DOI: 10.1103/PhysRevLett.110.017401X112723Nsciescopu

Neuromorphic Character Recognition System With Two PCMO Memristors as a Synapse

Using memristor devices as synaptic connections has been suggested with different neural architectures in the literature. Most of the published works focus on simulating some plasticity mechanism for changing memristor conductance. This paper presents a neural architecture of a character recognition neural system using Al/Pr0.7Ca0.3MnO3 (PCMO) memristors. The PCMO memristor has an inhomogeneous barrier at the aluminum and PCMO interface which gives rise to an asymmetrical behavior when moving from high resistance to low resistance and vice versa. This paper details the design and simulations for solving this asymmetrical memristor behavior. Also, a general memory read/write framework is used to describe the running and plasticity of neural systems. The proposed neural system can be produced in hardware using a small 1 K crossbar memristor grid and CMOS neural nodes as presented in the simulation results.X111917Ysciescopu

On heart rate regulation in cycle-ergometer exercise

© 2014 IEEE. In this paper, we have focused on the issue of regulating the human heart rate (HR) to a predefined reference trajectory, especially for cycle-ergometer exercise used for training or rehabilitation. As measuring HR is relatively easy compared to exercise intensity, it has been used in the wide range of training programs. The aim of this paper is to develop a non-model-based control strategy using proportional, integral and derivative (PID) controller/relay controller to regulate the HR to track a desired trajectory. In the case of using PID controller, the controller output signal is interpreted as a voice or auditory command, referred to as biofeedback, which can be heard by the exercising subject as a part of the control-loop. Alternatively, the relay controller output signals can be converted to some special words which can be recognised by the exerciser. However, in both cases, to effectively communicate to the user a change in exercise intensity, the timing of this feedback signal relative to the positions of the pedals becomes quite critical. A feedback signal delivered when the pedals are not in a suitable position to efficiently exert force may be ineffective and may lead to a cognitive disengagement of the user form the feedback controller. In this paper we examine the need and the consequence of synchronising the delivery of the feedback signal with an optimal and user specific placement of the pedal

An experimental and numerical study on nonlinear impact responses of steel-plated structures in an Arctic environment

Ships and offshore platforms that operate in Arctic regions at low temperatures are likely subjected to impact loads that arise from collisions with icebergs. The aim of this paper was to examine the nonlinear impact response of steel-plated structures in an Arctic environment. In addition to material tensile tests for characterisation of the mechanical properties of polar-class high-tensile steel of grade DH36, an experimental study was undertaken in a dropped-object test facility on steel-plated structure models under impact loads and at low temperatures equivalent to those in Arctic regions. LS-DYNA nonlinear finite element computations were also performed for the corresponding test models. We conclude that nonlinear finite element analyses are useful in the analysis of the nonlinear impact structural responses involving yielding, crushing and brittle fracture at low temperatures as long as the modelling techniques are adequate. The conclusions and insights developed in this paper should be useful in the safety design of ships and offshore platforms intended for operation in Arctic regions

Effect of farnesyltransferase inhibitor R115777 on mitochondria of plasmodium falciparum

The parasite Plasmodium falciparum causes severe malaria and is the most dangerous to humans. However, it exhibits resistance to their drugs. Farnesyltransferase has been identified in pathogenic protozoa of the genera Plasmodium and the target of farnesyltransferase includes Ras family. Therefore, the inhibition of farnesyltransferase has been suggested as a new strategy for the treatment of malaria. However, the exact functional mechanism of this agent is still unknown. In addition, the effect of farnesyltransferase inhibitor (FTIs) on mitochondrial level of malaria parasites is not fully understood. In this study, therefore, the effect of a FTI R115777 on the function of mitochondria of P. falciparum was investigated experimentally. As a result, FTI R115777 was found to suppress the infection rate of malaria parasites under in vitro condition. It also reduces the copy number of mtDNA-encoded cytochrome c oxidase III. In addition, the mitochondrial membrane potential (Delta psi m) and the green fluorescence intensity of MitoTracker were decreased by FTI R115777. Chloroquine and atovaquone were measured by the mtDNA copy number as mitochondrial non-specific or specific inhibitor, respectively. Chloroquine did not affect the copy number of mtDNA-encoded cytochrome c oxidase III, while atovaquone induced to change the mtDNA copy number. These results suggest that FTI R115777 has strong influence on the mitochondrial function of P. falciparum. It may have therapeutic potential for malaria by targeting the mitochondria of parasites.1133Ysciescopu

Bright spots, physical activity investments that work : sweatcoin : a steps generated virtual currency for sustained physical activity behaviour change

Sweatcoin converts the step count recorded on smartphones into a virtual currency. Using this app, users generate financial rewards through physical activity, with higher levels of activity creating a higher ‘income’. Sweatcoins can subsequently be used to purchase commercially available products from an in-app marketplace